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产品分类 > 花粉过敏原 > Natural Amb a 1 豚草过敏原Amb a 1

Natural Amb a 1 豚草过敏原Amb a 1

产品货号:NA-AAR1-1
促销: 9200.00
价格: 9200.00

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250ug
美国Indoor
Allergen:nAmb a 1 (Ambrosia artemisiifolia allergen 1),Short ragweed
Unit:250 µg

Source:Short ragweed pollen (Ambrosia artemisiifolia)

Mol. Wt:38-40 kDa

Purification:

From delipidated short ragweed extract by multi-step chromatography.

Purity > 95 % by silver stained SDS-PAGE

Concentration:See product insert.

Formulation:

Preservative-free and carrier-free in phosphate buffered

saline, pH 7.4. Filtered through 0.22µ filter.

Storage:Store at -20ºC

Notes:Natural Amb a 1 undergoes proteolysis during purification and is cleaved into two non-covalently associated chains of ~25kD (α-chain)

and 16kD (β-chain).

PDB:
Product Resources:Natural Amb a 1 Certificate of Analysis

Allergens are provided for research and commercial use in vitro: Not for human in vivo or therapeutic use.

References:


  1. Jahn-Schmid B, Wopfner N, Hubinger G, Asero R, Ebner C, Ferreira F, Bohle B. The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements. J Allergy Clin Immunol 2010; 126(5):1068-1071.

  2. Rafnar T, Griffith IJ, Kuo MC, Bond JF, Rogers BL, Klapper DG. Cloning of Amb a I (antigen E), the major allergen family of short ragweed pollen. J Biol Chem 1991; 266(2):1229-1236.

  3. Wopfner N, Bauer R, Thalhamer J, Ferreira F, Chapman M. Immunologic analysis of monoclonal and immunoglobulin E antibody epitopes on natural and recombinant Amb a 1. Clin Exp Allergy 2008; 38(1):219-226.

  4. King TP, Norman PS. Isolation of allergens from ragweed pollen. Biochemistry 1962; 1:709–720.