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产品分类 > 食物过敏原 > Natural Ara h 2 花生过敏原Ara h2

Natural Ara h 2 花生过敏原Ara h2

产品货号:NA-AH2-1
促销: 9520.00
价格: 9520.00

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250ug
美国Indoor
Allergen:nAra h 2 (Arachis hypogaea allergen 2)

Unit:250µg

Source:Light roasted peanut flour (Runner cultivar)

Mol. Wt:17-19 kD doublet

Purification:

From delipidated peanut extract by multi-step chromatography. Purity on silver stained SDS-PAGE >95%.

Concentration:See Product Insert.

Formulation:

Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Sterile filtered.

Storage:Store at -20ºC

Notes:

(1) Ara h 2 appears as a doublet. (2) Trace level of Ara h 1 is <0.05% (3) Endotoxin content is < 5.0 EU/μg.

PDB:
Product Resources:Natural Ara h 2 Certificate of Analysis

Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.

References:


  1. Burks AW, Williams LW, Connaughton C, Cockrell G, O’Brien TJ, Helm RM. Identification and characterization of a second major peanut allergen, Ara h II, with use of the sera of patients with atopic dermatitis and positive peanut challenge. J Allergy Clin Immunol 1992;90:962-9.

  2. Sen M, Kopper R, Pons L, Abraham EC, Burks W, Bannon GA. Protein structure plays a critical role in peanut allergen stability and may determine immunodominant IgE-Binding epitopes. J Immunol 2002;169:882-7.

  3. Maleki SJ, Viquez O, Jacks T, Dodo H, Champagne ET, Chung SY, Landry SJ. The major peanut allergen, Ara h 2, functions as a trypsin inhibitor, and roasting enhances this function. J Allergy Clin Immunol, 2003;112:190-195.

  4. Flinterman AE, van Hoofen E, den Hartog Jager CF, Koppelman S, Pasmans SG, Hoekstra MO, Bruijnzeel-Koomen CA, Knulst AC, Knol EF. Children with peanut allergy recognize predominantly Ara h2 and Ara h 6, which remains stable over time. Clin Exp Allergy 2007;37:1221-8.

  5. McDermott RA, Porterfield HS, El Mezayen R, Burks AW, Pons L, Schlichting DG, Solomon B, Redzic, JS, Harbeck RJ, Duncan MW, Hansen KC, Dreskin SC. Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation. Clin Exp Allergy 2007;37:752-763.